Show simple item record

dc.contributor.authorKruger, Ruan
dc.contributor.authorMonyeki, Makama Andries
dc.contributor.authorSchutte, Aletta Elisabeth
dc.contributor.authorSmith, Wayne
dc.contributor.authorMels, Catharina Martha Cornelia
dc.contributor.authorKruger, Herculina Salomé
dc.contributor.authorPienaar, Anita Elizabeth
dc.contributor.authorGafane-Matemane, Lebo Francina
dc.contributor.authorBreet, Yolandi
dc.contributor.authorLammertyn, Leandi
dc.contributor.authorMokwatsi, Gontse Gratitude
dc.contributor.authorKruger, Ankebé
dc.contributor.authorDeacon, Elmari
dc.date.accessioned2020-08-20T08:12:39Z
dc.date.available2020-08-20T08:12:39Z
dc.date.issued2020
dc.identifier.citationKruger, R. et al. 2020. The Exercise, Arterial Modulation and Nutrition in Youth South Africa Study (ExAMIN Youth SA). Frontiers in pediatrics, 8: #212. [https://doi.org/10.3389/fped.2020.00212]en_US
dc.identifier.issn2296-2360 (Online)
dc.identifier.urihttp://hdl.handle.net/10394/35603
dc.identifier.urihttps://www.frontiersin.org/articles/10.3389/fped.2020.00212/pdf
dc.identifier.urihttps://doi.org/10.3389/fped.2020.00212
dc.description.abstractBackground: The impact of a sedentary and unhealthy lifestyle on cardiovascular health is well-documented, however the current obesity and hypertension trends among children is concerning. The ExAMIN Youth SA study aims to investigate the impact of lifestyle behaviors (physical fitness/activity, dietary intake and psychosocial factors) involved in early vascular aging among South African children. Methods: This study is an analytical, multidisciplinary, observational cohort study in a school-based setting. We aim to phenotype a cohort of ∼1,000 primary school children (black and white boys and girls between ages 5–9 years) based on current clinical childhood conditions including hypertension and obesity. The primary phenotype is large artery stiffness and retinal microvascular diameters, both biomarkers of early vascular aging. The risk factors and mediators of early vascular aging and also responsible for the clinical conditions include physical inactivity, unhealthy diet, and life stress. Additionally, urinalysis and salivary analyses will be performed to identify biomarkers related to the pathophysiology of early vascular aging. Discussion: In line with the growing prevalence of obesity and hypertension responsible for the development of early vascular aging from childhood to adulthood, this study will address the critical areas in which we observe unfavorable arterial modulation related to dietary behaviors, physical inactivity, and early life stress. Implementation of novel biological markers may further contribute to our understanding of early cardiovascular adaptations in childhood, and aid in the development of primary prevention programsen_US
dc.language.isoenen_US
dc.publisherFrontiers Mediaen_US
dc.subjectChild healthen_US
dc.subjectBlood pressureen_US
dc.subjectObesityen_US
dc.subjectArterial stiffnessen_US
dc.subjectRetinal vessel diametersen_US
dc.subjectNutritionen_US
dc.subjectPhysical activityen_US
dc.subjectPsychosocial behavioren_US
dc.titleThe Exercise, Arterial Modulation and Nutrition in Youth South Africa Study (ExAMIN Youth SA)en_US
dc.typeArticleen_US
dc.contributor.researchID20035632 - Kruger, Ruan
dc.contributor.researchID12621595 - Monyeki, Makama Andries
dc.contributor.researchID10922180 - Schutte, Aletta Elisabeth
dc.contributor.researchID22945717 - Smith, Wayne
dc.contributor.researchID12076341 - Mels, Catharina Martha Cornelia
dc.contributor.researchID10061568 - Kruger, Herculina Salome
dc.contributor.researchID10063153 - Pienaar, Anita Elizabeth
dc.contributor.researchID24341185 - Gafane-Matemane, Lebo Francina
dc.contributor.researchID21195706 - Breet, Yolandi
dc.contributor.researchID20088310 - Lammertyn, Leandi
dc.contributor.researchID22368590 - Mokwatsi, Gontse Gratitude
dc.contributor.researchID11755350 - Kruger, Ankebé
dc.contributor.researchID10857729 - Deacon, Elmari


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record