White rice intake and incident diabetes: a study of 132,373 participants in 21 countries
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Date
2020Author
Bhavadharini, Balaji
Wentzel-Viljoen, Edelweiss
Mohan, Viswanathan
Dehghan, Mahshid
Rangarajan, Sumathy
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Show full item recordAbstract
OBJECTIVE
Previous prospective studies on the association of white rice intake with incident
diabetes have shown contradictory results but were conducted in single countries
and predominantly in Asia. We report on the association of white rice with risk of
diabetes in the multinational Prospective Urban Rural Epidemiology (PURE) study.
RESEARCH DESIGN AND METHODS
Data on 132,373 individuals aged 35–70 years from 21 countries were analyzed.
White rice consumption (cooked) was categorized as <150, ‡150 to <300, ‡300
to <450, and ‡450 g/day, based on one cup of cooked rice 5 150 g. The primary
outcome was incident diabetes. Hazard ratios (HRs) were calculated using a
multivariable Cox frailty model.
RESULTS
During a mean follow-up period of 9.5 years, 6,129 individuals without baseline
diabetes developed incident diabetes. In the overall cohort, higher intake of white
rice (‡450 g/day compared with <150 g/day) was associated with increased risk of
diabetes (HR 1.20; 95% CI 1.02–1.40; P for trend 5 0.003). However, the highest risk
was seen in South Asia (HR 1.61; 95% CI 1.13–2.30; P for trend 5 0.02), followed by
other regions of the world (which included South East Asia, Middle East, South
America, North America, Europe, and Africa) (HR 1.41; 95% CI 1.08–1.86; P for
trend 5 0.01), while in China there was no significant association (HR 1.04; 95% CI
0.77–1.40; P for trend 5 0.38).
CONCLUSIONS
Higher consumption of white rice is associated with an increased risk of incident
diabetes with the strongest association being observed in South Asia, while in other
regions, a modest, nonsignificant association was seen
URI
http://hdl.handle.net/10394/36280https://care.diabetesjournals.org/content/43/11/2643
https://doi.org/10.2337/dc19-2335
Collections
- Faculty of Health Sciences [2385]