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    Influence of the composition of water/ethanol mixtures on the solubility and recrystallization of nevirapine

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    Date
    2010
    Author
    Stieger, Nicole
    Liebenberg, Wilna
    Tiedt, Louwrens R.
    Wessels, Johanna C.
    Caira, Mino R.
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    Abstract
    Anhydrous nevirapine was recrystallized from ethanol containing various amounts of water to determine its effects on the products obtained. The solubility of the anhydrous form was determined for each of the binary solvent systems, and compared to the composition of the solvent system. A novel hemiethanolate was fully characterized by thermal methods, FT-IR spectroscopy, and single crystal X-ray diffraction
    URI
    http://hdl.handle.net/10394/6179
    https://pubs.acs.org/doi/abs/10.1021/cg901501d
    https://doi.org/10.1021/cg901501d
    Collections
    • Faculty of Health Sciences [2368]
    • Faculty of Natural and Agricultural Sciences [4789]

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