Browsing Research Output by Title

Bio-oil production from sweet sorghum bagasse via liquefaction using alkaline solutions and identification of phenolic products

Sehume, Thabo Z.; Strydom, Christien A.; Bunt, John R.; Schobert, Harold H. (Springer, 2020)

The feasibility of converting biomass into bio-oil and the effect of an alkaline treatment during biomass liquefaction was studied. Sweet sorghum bagasse (SSB) was treated with NaOH concentrations of 0.5, 1.0, 3.0 and 6.0 ...

Bioaccessibility and risk assessment of essential and non-essential elements in vegetables commonly consumed in Swaziland

Mnisi, Robert Londi; Mafu, Lihle D.; Ndibewu, Peter P.; Bwembya, Gabriel C. (Elsevier, 2017)

The green leafy vegetables (Mormodica involucrate, Bidens pilosa and Amaranthus spinosus) are economic; seasonal; locally grown and easily available; easy to propagate and store; highly nutritious food substances that form ...

Bioaccumulation and human health risk assessment of DDT and other organochlorine pesticides in an apex aquatic predator from a premier conservation area

Gerber, Ruan; Smit, Nico; Ikenaka, Yoshinori; Wepener, Victor; Van Vuren, Johan H.J. (Elsevier, 2016)

With the second highest gross domestic product in Africa, South Africa is known to have a high pesticide usage, including the highly persistent and banned group of organochlorine pesticides (OCPs). South Africa is also one ...

Bioaccumulation and metal-associated biomarker responses in a freshwater mussel, Dreissena polymorpha, following short-term platinum exposure

Brand, Sarel J.; Erasmus, Johannes H.; Labuschagne, Marelize; Wepener, Victor; Smit, Nico (Elsevier, 2019)

Due to the increasing presence of platinum (Pt) in the environment, the caveat arises to identify its toxic potential in species at risk of being exposed – especially those found in aquatic environments where pollutants ...

Bioaccumulation and subchronic toxicity of 14 nm gold nanoparticles in rats

Rambanapasi, Clinton; Zeevaart, Jan Rijn; Buntting, Hylton; Bester, Cornelius; Hayeshi, Rose; Grobler, Anne (MDPI, 2016)

Colloidal suspensions of 14 nm gold nanoparticles (AuNPs) were repeatedly administered intravenously at three dose levels (0.9, 9 and 90 µg) to male Sprague Dawley rats weekly for 7 weeks, followed by a 14-day washout ...

Bioaccumulation and trophic transfer of total mercury in the subtropical Olifants River Basin, South Africa

Verhaert, Vera; Vlok, Wynand; Wepener, Victor; Teuchies, Johannes; Addo-Bediako, Abraham (Elsevier, 2019)

The present study describes total mercury (THg) levels in surface water, sediment and biota from the Olifants River Basin (ORB) (South Africa) and investigates the trophic transfer of THg by means of trophic magnification ...

Bioaccumulation of persistent organic pollutants and their trophic transfer through the food web: human health risks to the rural communities reliant on fish from South Africa's largest floodplain

Volschenk, C.M.; Gerber, R.; Ikenaka, Y.; Van Vuren, J.H.J.; Wepener, V.; Smit, N.J. (Elsevier, 2019)

The Phongolo River Floodplain (PRF) is South Africa's largest floodplain, unique in being the only large floodplain able to sustain permanent waters throughout the dry season (Kyle, 2002). This highly productive region ...

Bioactive albumin-based carriers for tumour chemotherapy

Shahzad, Yasser; Gerber, Minja; Du Plessis, Jeanetta; Khan, Ikram U.; Hussain, Talib (Bentham Science, 2014)

Proteins are posed as the natural counterpart of the synthetic polymers for the development of drug delivery systems and few of them, have been regarded safe for drug delivery purposes by the United States Food and Drug ...

Bioavailable IGF-1 and its relation to the metabolic syndrome in a bi-ethnic population of men and women

Koegelenberg, A.S.E.; Schutte, R.; Smith, W.; Schutte, A.E. (Georg Thieme Verlag, 2016)

Insulin-like growth factor 1 (IGF-1), an insulin sensitivity and vasculoprotective factor, associates negatively with the metabolic syndrome. However, IGF-1 is reduced by factors such as inflammation, oxidative stress and ...

Bioavailable IGF-1 is beneficially associated with biomarkers of endothelial function in young healthy adults: the African-PREDICT study

Barnard, Sunelle A.; Smith, Wayne; Mels, Catharina M.C.; Botha, Shani; Schutte, Aletta E. (Elsevier, 2018)

Low circulating levels of insulin-like growth factor-1 (IGF-1) are associated with endothelial dysfunction, subsequently leading to the development of cardiovascular disease. Objective To better understand the early ...

Biobanks in South Africa: a global perspective on privacy and confidentiality

Rheeder, R. (Health and Medical Publishing Group (HMPG), 2017)

The Universal Declaration of Bioethics and Human Rights (UDBHR) of the United Nations Educational, Scientific and Cultural Organization (UNESCO) was adopted unanimously in 2005 by the world community as a universal guideline, ...

Biocide resistant and antibiotic cross-resistant potential pathogens from sewage and river water from a wastewater treatment facility in the North-West, Potchefstroom, South Africa

Mann, B.C.; Bezuidenhout, J.J.; Bezuidenhout, C.C. (IWA Publishing, 2019)

Exposure to antibiotics, biocides, chemical preservatives, and heavy metals in different settings such as wastewater treatment plants (WWTPs) may apply selective pressure resulting in the enrichment of multiple resistant, ...

Biocompositional and thermodecompositional analysis of South African agro-waste corncob and husk towards production of biocommodities

Awosusi, Ayotunde A.; Adeleke, R.; Ayeni, Augustine O.; Daramola, Michael O. (Wiley, 2017)

Biocompositional and thermodecompositional analyses of locally abundant agro-wastes of South African corn were evaluated for their potential utilization as biocommodities via thermochemical and bioconversion processing. ...

Biodistribution (as determined by the radiolabelled equivalent) of a gold(III) bis(pyrrolide-imine) Schiff base complex: a potential chemotherapeutic

Akerman, Matthew P.; Bester, Cornelius J.; Zeevaart, Jan Rijn; Munro, Orde Q.; Mongane, Modisenyane (Wiley, 2013)

The biodistribution of an N2N2 0 tetradentate gold(III) chelate, which is known to be cytotoxic towards a range of human cancer cell lines, was determined by a radiolabelled equivalent of the compound. The 198Au-labelled ...

Biodistribution and dosimetry of 195mPt-cisplatin in normal volunteers

Sathekge, M.; Zeevaart, J.R.; Wagener, J.; Smith, S.V.; Soni, N. (Schattauer, 2013)

195mPt-cisplatin is regarded as a promising imaging agent for optimizing dosage in patients receiving cisplatin chemotherapy. We investigated the whole-body distribution and radiation dosimetry of 195mPt-cisplatin in ...

Biodistribution and pharmacokinetics of I-131 labelled 4- Iodophenylacetic acid

Zeevaart, Jan Rijn; Szucs, Zoltan; Pulker, Tamsyn; Sello, Thato; Bracher, Jacqueline (Bentham Science, 2012)

Abstract: Phenylacetate has been reported to have a potent anti-proliferative and anti-differentiating effect in haematological malignancies and in solid tumours at non-toxic concentrations. This study is a preliminary ...

Biodistribution of a potential chemotherapeutic, dinuclearbisphosphinogold(I) dithiocarbamate, as determined by its 198Au radiolabelled analogue

Kriel, Frederik H.; Bester, Cornelius J.; Zeevaart, Jan Rijn; Szucs, Zoltan; Van Staden, Johan A. (Springer, 2015)

Dinuclearbisphosphinogold(I) dithiocarbamato, BPDTC, was previously found to have antitumour activity in vitro. 198Au radiolabelled BPDTC (radiochemical yield of 70 ± 6 % and radiochemical purity of[95 %) was used to ...