Browsing Faculty of Health Sciences by Author "Franken, A."

Now showing items 1-6 of 6

    • Dermal exposure and changes in skin barrier function of base metal refinery workers co-exposed to cobalt and nickel 

      Du Plessis, J.L.; Eloff, F.C.; Engelbrecht, S.; Laubscher, P.J.; Van Aarde, M.N.; Franken, A. (The South African Society of Occupational Medicin, 2013)
      Refi nery workers are exposed to many metals, including cobalt and nickel, both of which are skin sensitisers, causing allergic contact dermatitis. Dermal exposure, and changes in skin barrier function [skin hydration, ...

    • DNA damage and repair capacity in hairdressers exposed to chemical products: a pilot study 

      Eloff, F.C.; Preston, R.; Pretorius, P.J.; Du Plessis, J.L.; Laubscher, P.J.; Van Aarde, M.N.; Van der Westhuizen, F.H.; Franken, A. (SASOM, 2013)
      Hairdressers are exposed to numerous hazardous chemical substances, some of which are known or suspected allergens, carcinogens or organic solvents. The objectives of this study were to compare DNA damage and DNA repair ...

    • The evaluation and quantification of respirable coal and silica dust concentrations: a task-based approach 

      Grové, T.; Franken, A.; Du Plessis, J.; Van Dyk, T. (Taylor & Francis, 2014)
      Silicosis and coal worker's pneumoconiosis are serious occupational respiratory diseases associated with the coal mining industry and the inhalation of respirable dusts containing crystalline silica. The purpose of this ...

    • In vitro permeation of platinum and rhodium through Caucasian skin 

      Franken, A.; Eloff, F.C.; Du Plessis, J.; Badenhorst, C.J.; Jordaan, A.; Du Plessis, J.L. (Elsevier, 2014)
      During platinum group metals (PGMs) refining the possibility exists for dermal exposure to PGM salts. The dermal route has been questioned as an alternative route of exposure that could contribute to employee sensitisation, ...

    • In vitro permeation of platinum through African and Caucasian skin 

      Franken, A.; Eloff, F.C.; Du Plessis, J.; Badenhorst, C.J.; Du Plessis, J.L. (Elsevier, 2015)
      The majority of the South African workforce are Africans, therefore potential racial differences should be considered in risk and exposure assessments in the workplace. Literature suggests African skin to be a superior ...

    • Reflections on the OECD guidelines for in vitro skin absorption studies 

      Hopf, N.B.; Du Plessis, J.L.; Franken, A.; Frasch, F.; Champmartin, C.; Schenk, L.; Berthet, A.; Chedik, L.; Gaskin, S. (Elsevier, 2020)
      At the 8th conference of Occupational and Environmental Exposure of the Skin to Chemicals (OEESC) (16–18 September 2019) in Dublin, Ireland, several researchers performing skin permeation assays convened to discuss in vitro ...